AMPHICHOLINE | American Pharmaceutical Innovations Company


Last Updated: Monday, January 30, 2023

A choline chloride source and a lipotropic agent for poultry and livestock to improve growth and performance and for better milk production and quality in dairy cattle.


Betaine Hydrochloride ≤ 96%

Product Description

  • AMPHICHOLINE HCL is a water-soluble colorless compound with vitamin-like properties as not a metabolic catalyst but forms an essential structural component of body tissues. Choline is ubiquitously distributed in all plant and animal cells, mostly in the form of the phospholipids, phosphatidylcholine (lecithin), lysophosphatidylcholine, choline plasmalogens and sphingomyelin - essential components of all membranes.
  • AMPHICHOLINE HCL powder is designed to ensure adequate choline chloride supplementation required for normal functioning, growth, production and feed efficiency in poultry and rumen protected choline improves milk yield and milk fat and reduce blood serum non-esterified fatty acids and cholesterol in dairy cattle and buffaloes.
  • Functions of choline chloride are:
  • Building and maintaining cell structures: Choline is a structural part of lecithin (phosphatidylcholine), certain plasmalogens and the sphingomyelins. Choline is required as a constituent of the phospholipids needed for normal maturation of the cartilage matrix of the bone.
  • Fat metabolism of the liver: Choline is referred to as a "lipotropic" factor due to its function of acting on fat metabolism by hastening removal or decreasing deposition of fat in liver. It prevents abnormal accumulation of fat (fatty livers) by promoting its transport as lipoprotein and lecithin or by increasing the utilization of fatty acids in the liver.
  • Formation of acetylcholine (essential): Choline is essential for the synthesis of acetylcholine by mitochondria at the presynaptic terminal of the neural synapse, a substance that makes possible the transmission of nerve impulses.
  • Methyl-group donor (non-essential) via betaine: Choline furnishes labile methyl groups for formation of methionine from homocysteine and of creatine from guanidoacetic acid.
  • The young chicken needs choline more due to inability to synthesize at sufficient rate. Females are less susceptible to choline deficiency, without exact clear mechanism.
  • Choline is highly required by dairy cattle and buffaloes. Choline is lipotropic factor, transport fat from liver and improves production. The earliest investigations with unprotected choline reveal neither milk production nor milk composition was improved may be due to rapid choline degradation in the rumen.

Product Benefits

  • AMPHICHOLINE HCL powder is added to poultry feed to promote growth, improve feed efficiency and feed conversion ratio.
  • AMPHICHOLINE HCL powder is used in young chicks to compensate for choline insufficient synthesis.
  • AMPHICHOLINE HCL powder is used in dairy cattle and buffaloes to improve milk yield and milk fat and reduce blood serum non-esterified fatty acids and cholesterol.
  • AMPHICHOLINE HCL powder is used in livestock as a "lipotropic factor" to guard against fatty liver.